diff --git a/DynamicTablesPkg/DynamicTables.dsc.inc b/DynamicTablesPkg/DynamicTables.dsc.inc
index 0f5ebace55..bc03c09d6c 100644
--- a/DynamicTablesPkg/DynamicTables.dsc.inc
+++ b/DynamicTablesPkg/DynamicTables.dsc.inc
@@ -10,6 +10,7 @@
 [Defines]
 
 [BuildOptions]
+  RELEASE_*_*_CC_FLAGS     = -DMDEPKG_NDEBUG
 
 [LibraryClasses.common]
   TableHelperLib|DynamicTablesPkg/Library/Common/TableHelperLib/TableHelperLib.inf