diff --git a/MdeModulePkg/Core/Dxe/DxeMain/DxeMain.c b/MdeModulePkg/Core/Dxe/DxeMain/DxeMain.c
index 83f49d7c00..0a1f3d79e2 100644
--- a/MdeModulePkg/Core/Dxe/DxeMain/DxeMain.c
+++ b/MdeModulePkg/Core/Dxe/DxeMain/DxeMain.c
@@ -256,6 +256,14 @@ DxeMain (
   Status = InitializeCpuExceptionHandlers (VectorInfoList);
   ASSERT_EFI_ERROR (Status);
 
+  //
+  // Setup Stack Guard
+  //
+  if (PcdGetBool (PcdCpuStackGuard)) {
+    Status = InitializeSeparateExceptionStacks (NULL);
+    ASSERT_EFI_ERROR (Status);
+  }
+
   //
   // Initialize Debug Agent to support source level debug in DXE phase
   //