diff --git a/MdeModulePkg/Universal/RegularExpressionDxe/Oniguruma/regparse.c b/MdeModulePkg/Universal/RegularExpressionDxe/Oniguruma/regparse.c
index c71ae5fa70..0a2d6f89e5 100644
--- a/MdeModulePkg/Universal/RegularExpressionDxe/Oniguruma/regparse.c
+++ b/MdeModulePkg/Universal/RegularExpressionDxe/Oniguruma/regparse.c
@@ -1572,6 +1572,7 @@ onig_set_callout_of_name(OnigEncoding enc, OnigCalloutType callout_type,
     fe->arg_types[i] = arg_types[i];
   }
   for (i = arg_num - opt_arg_num, j = 0; i < arg_num; i++, j++) {
+    if(IS_NULL(opt_defaults))return ONIGERR_INVALID_ARGUMENT;
     if (fe->arg_types[i] == ONIG_TYPE_STRING) {
       OnigValue* val = opt_defaults + j;
       UChar* ds = onigenc_strdup(enc, val->s.start, val->s.end);