diff --git a/MdePkg/Include/Library/SynchronizationLib.h b/MdePkg/Include/Library/SynchronizationLib.h
index 7b97683ca0..6cf3d71770 100644
--- a/MdePkg/Include/Library/SynchronizationLib.h
+++ b/MdePkg/Include/Library/SynchronizationLib.h
@@ -1,7 +1,7 @@
 /** @file
   Provides synchronization functions.
 
-Copyright (c) 2006 - 2012, Intel Corporation. All rights reserved.<BR>
+Copyright (c) 2006 - 2016, Intel Corporation. All rights reserved.<BR>
 This program and the accompanying materials
 are licensed and made available under the terms and conditions of the BSD License
 which accompanies this distribution.  The full text of the license may be found at
@@ -157,7 +157,7 @@ ReleaseSpinLock (
 UINT32
 EFIAPI
 InterlockedIncrement (
-  IN      UINT32                    *Value
+  IN      volatile UINT32           *Value
   );
 
 
@@ -179,7 +179,7 @@ InterlockedIncrement (
 UINT32
 EFIAPI
 InterlockedDecrement (
-  IN      UINT32                    *Value
+  IN      volatile UINT32           *Value
   );
 
 
@@ -204,7 +204,7 @@ InterlockedDecrement (
 UINT16
 EFIAPI
 InterlockedCompareExchange16 (
-  IN OUT  UINT16                    *Value,
+  IN OUT  volatile UINT16           *Value,
   IN      UINT16                    CompareValue,
   IN      UINT16                    ExchangeValue
   );
@@ -231,7 +231,7 @@ InterlockedCompareExchange16 (
 UINT32
 EFIAPI
 InterlockedCompareExchange32 (
-  IN OUT  UINT32                    *Value,
+  IN OUT  volatile UINT32           *Value,
   IN      UINT32                    CompareValue,
   IN      UINT32                    ExchangeValue
   );
@@ -258,7 +258,7 @@ InterlockedCompareExchange32 (
 UINT64
 EFIAPI
 InterlockedCompareExchange64 (
-  IN OUT  UINT64                    *Value,
+  IN OUT  volatile UINT64           *Value,
   IN      UINT64                    CompareValue,
   IN      UINT64                    ExchangeValue
   );
@@ -285,7 +285,7 @@ InterlockedCompareExchange64 (
 VOID *
 EFIAPI
 InterlockedCompareExchangePointer (
-  IN OUT  VOID                      **Value,
+  IN OUT  VOID                      * volatile *Value,
   IN      VOID                      *CompareValue,
   IN      VOID                      *ExchangeValue
   );