diff --git a/MdeModulePkg/Core/Dxe/Hand/Handle.c b/MdeModulePkg/Core/Dxe/Hand/Handle.c
index 3ed187b279..2db441725c 100644
--- a/MdeModulePkg/Core/Dxe/Hand/Handle.c
+++ b/MdeModulePkg/Core/Dxe/Hand/Handle.c
@@ -1178,6 +1178,7 @@ Done:
       // EFI_ALREADY_STARTED is not an error for bus driver.
       // Return the corresponding protocol interface.
       //
+      ASSERT (Prot != NULL);
       *Interface = Prot->Interface;
     } else if (Status == EFI_UNSUPPORTED) {
       //