diff --git a/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.S b/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.S
index 3ad22bd570..0d802d6928 100644
--- a/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.S
+++ b/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.S
@@ -125,7 +125,8 @@ ASM_PFX(MmioWrite32Internal):
 //  @return The value read.
 //
 ASM_PFX(MmioRead64Internal):
-  ldrd    r0, r1, [r0]
+  ldr     r1, [r0, #4]
+  ldr     r0, [r0]
   dmb
   bx      lr
 
@@ -141,5 +142,6 @@ ASM_PFX(MmioRead64Internal):
 //
 ASM_PFX(MmioWrite64Internal):
   dmb     st
-  strd    r2, r3, [r0]
+  str     r2, [r0]
+  str     r3, [r0, #4]
   bx      lr
diff --git a/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.asm b/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.asm
index e1a3d68a43..deba8c1f0c 100644
--- a/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.asm
+++ b/MdePkg/Library/BaseIoLibIntrinsic/Arm/ArmVirtMmio.asm
@@ -127,7 +127,8 @@ MmioWrite32Internal
 ;  @return The value read.
 ;
 MmioRead64Internal
-  ldrd    r0, r1, [r0]
+  ldr     r1, [r0, #4]
+  ldr     r0, [r0]
   dmb
   bx      lr
 
@@ -143,7 +144,8 @@ MmioRead64Internal
 ;
 MmioWrite64Internal
   dmb     st
-  strd    r2, r3, [r0]
+  str     r2, [r0]
+  str     r3, [r0, #4]
   bx      lr
 
   END