diff --git a/CryptoPkg/Library/OpensslLib/OpensslLibCrypto.inf b/CryptoPkg/Library/OpensslLib/OpensslLibCrypto.inf
index c4eaea888c..f408687461 100644
--- a/CryptoPkg/Library/OpensslLib/OpensslLibCrypto.inf
+++ b/CryptoPkg/Library/OpensslLib/OpensslLibCrypto.inf
@@ -611,8 +611,8 @@
   #    1: ignore "#1-D: last line of file ends without a newline"
   # 3017: <entity> may be used before being set (NOTE: This was fixed in OpenSSL 1.1 HEAD with
   #       commit d9b8b89bec4480de3a10bdaf9425db371c19145b, and can be dropped then.)
-  XCODE:*_*_IA32_CC_FLAGS   = -mmmx -msse -U_WIN32 -U_WIN64 $(OPENSSL_FLAGS) $(OPENSSL_FLAGS_CONFIG) -w -std=c99 -Wno-error=uninitialized
-  XCODE:*_*_X64_CC_FLAGS    = -mmmx -msse -U_WIN32 -U_WIN64 $(OPENSSL_FLAGS) $(OPENSSL_FLAGS_CONFIG) -w -std=c99 -Wno-error=uninitialized
+  XCODE:*_*_IA32_CC_FLAGS   = -mmmx -msse -U_WIN32 -U_WIN64 $(OPENSSL_FLAGS) $(OPENSSL_FLAGS_CONFIG) -w -std=c99 -Wno-error=uninitialized -DOPENSSL_NO_APPLE_CRYPTO_RANDOM
+  XCODE:*_*_X64_CC_FLAGS    = -mmmx -msse -U_WIN32 -U_WIN64 $(OPENSSL_FLAGS) $(OPENSSL_FLAGS_CONFIG) -w -std=c99 -Wno-error=uninitialized -DOPENSSL_NO_APPLE_CRYPTO_RANDOM
 
   #
   # AARCH64 uses strict alignment and avoids SIMD registers for code that may execute