diff --git a/MdePkg/Library/BaseSynchronizationLib/BaseSynchronizationLib.inf b/MdePkg/Library/BaseSynchronizationLib/BaseSynchronizationLib.inf
index 6f7f24b2c8..0df1ddbedb 100755
--- a/MdePkg/Library/BaseSynchronizationLib/BaseSynchronizationLib.inf
+++ b/MdePkg/Library/BaseSynchronizationLib/BaseSynchronizationLib.inf
@@ -64,6 +64,7 @@
X64/InterlockedCompareExchange64.asm | INTEL
X64/InterlockedCompareExchange32.nasm| INTEL
X64/InterlockedCompareExchange32.asm | INTEL
+ X64/InterlockedCompareExchange16.nasm| INTEL
X64/InterlockedCompareExchange16.asm | INTEL
X64/InterlockedDecrement.c | MSFT
diff --git a/MdePkg/Library/BaseSynchronizationLib/X64/InterlockedCompareExchange16.nasm b/MdePkg/Library/BaseSynchronizationLib/X64/InterlockedCompareExchange16.nasm
new file mode 100644
index 0000000000..1d72d074f6
--- /dev/null
+++ b/MdePkg/Library/BaseSynchronizationLib/X64/InterlockedCompareExchange16.nasm
@@ -0,0 +1,42 @@
+;------------------------------------------------------------------------------
+;
+; Copyright (c) 2006, Intel Corporation. All rights reserved.
+; Copyright (c) 2015, Linaro Ltd. All rights reserved.
+; This program and the accompanying materials
+; are licensed and made available under the terms and conditions of the BSD License
+; which accompanies this distribution. The full text of the license may be found at
+; http://opensource.org/licenses/bsd-license.php.
+;
+; THE PROGRAM IS DISTRIBUTED UNDER THE BSD LICENSE ON AN "AS IS" BASIS,
+; WITHOUT WARRANTIES OR REPRESENTATIONS OF ANY KIND, EITHER EXPRESS OR IMPLIED.
+;
+; Module Name:
+;
+; InterlockedCompareExchange16.Asm
+;
+; Abstract:
+;
+; InterlockedCompareExchange16 function
+;
+; Notes:
+;
+;------------------------------------------------------------------------------
+
+ DEFAULT REL
+ SECTION .text
+
+;------------------------------------------------------------------------------
+; UINT16
+; EFIAPI
+; InterlockedCompareExchange16 (
+; IN UINT16 *Value,
+; IN UINT16 CompareValue,
+; IN UINT16 ExchangeValue
+; );
+;------------------------------------------------------------------------------
+global ASM_PFX(InternalSyncCompareExchange16)
+ASM_PFX(InternalSyncCompareExchange16):
+ mov ax, dx
+ lock cmpxchg [rcx], r8w
+ ret
+