diff --git a/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c b/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c
index f4e61d223c..cf6b32959e 100644
--- a/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c
+++ b/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c
@@ -825,7 +825,10 @@ XhcTransfer (
   *TransferResult = Urb->Result;
   *DataLength     = Urb->Completed;
 
-  if ((*TransferResult == EFI_USB_ERR_STALL) || (*TransferResult == EFI_USB_ERR_BABBLE)) {
+  //
+  // Based on XHCI spec 4.8.3, software should do the reset endpoint while USB Transaction occur.
+  //
+  if ((*TransferResult == EFI_USB_ERR_STALL) || (*TransferResult == EFI_USB_ERR_BABBLE) || (*TransferResult == EDKII_USB_ERR_TRANSACTION)) {
     ASSERT (Status == EFI_DEVICE_ERROR);
     RecoveryStatus = XhcRecoverHaltedEndpoint (Xhc, Urb);
     if (EFI_ERROR (RecoveryStatus)) {
diff --git a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c
index 5d735008ba..a97ed44dbf 100644
--- a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c
+++ b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c
@@ -1192,8 +1192,11 @@ XhcCheckUrbResult (
         DEBUG ((DEBUG_ERROR, "XhcCheckUrbResult: ERR_BUFFER! Completecode = %x\n", EvtTrb->Completecode));
         goto EXIT;
 
+      //
+      // Based on XHCI spec 4.8.3, software should do the reset endpoint while USB Transaction occur.
+      //
       case TRB_COMPLETION_USB_TRANSACTION_ERROR:
-        CheckedUrb->Result  |= EFI_USB_ERR_TIMEOUT;
+        CheckedUrb->Result  |= EDKII_USB_ERR_TRANSACTION;
         CheckedUrb->Finished = TRUE;
         DEBUG ((DEBUG_ERROR, "XhcCheckUrbResult: TRANSACTION_ERROR! Completecode = %x\n", EvtTrb->Completecode));
         goto EXIT;
diff --git a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h
index 7c85f7993b..e606e212a1 100644
--- a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h
+++ b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h
@@ -78,6 +78,13 @@ SPDX-License-Identifier: BSD-2-Clause-Patent
 #define TRB_COMPLETION_STOPPED                 26
 #define TRB_COMPLETION_STOPPED_LENGTH_INVALID  27
 
+//
+// USB Transfer Results Internal Definition
+// Based on XHCI spec 4.8.3, software should do the reset endpoint while USB Transaction occur.
+// Add the error code for USB Transaction error since UEFI spec don't have the related definition.
+//
+#define EDKII_USB_ERR_TRANSACTION  0x200
+
 //
 // The topology string used to present usb device location
 //