diff --git a/BaseTools/Source/Python/Workspace/MetaFileParser.py b/BaseTools/Source/Python/Workspace/MetaFileParser.py
index 1a5fdf5e62..37a7f5d1de 100644
--- a/BaseTools/Source/Python/Workspace/MetaFileParser.py
+++ b/BaseTools/Source/Python/Workspace/MetaFileParser.py
@@ -1,7 +1,7 @@
 ## @file
 # This file is used to parse meta files
 #
-# Copyright (c) 2008 - 2016, Intel Corporation. All rights reserved.<BR>
+# Copyright (c) 2008 - 2017, Intel Corporation. All rights reserved.<BR>
 # (C) Copyright 2015-2016 Hewlett Packard Enterprise Development LP<BR>
 # This program and the accompanying materials
 # are licensed and made available under the terms and conditions of the BSD License
@@ -351,6 +351,13 @@ class MetaFileParser(object):
 
         self._ValueList = [ReplaceMacro(Value, self._Macros) for Value in self._ValueList]
         Name, Value = self._ValueList[1], self._ValueList[2]
+        MacroUsed = GlobalData.gMacroRefPattern.findall(Value)
+        if len(MacroUsed) != 0:
+            for Macro in MacroUsed:
+                if Macro in GlobalData.gGlobalDefines:
+                    EdkLogger.error("Parser", FORMAT_INVALID, "Global macro %s is not permitted." % (Macro), ExtraData=self._CurrentLine, File=self.MetaFile, Line=self._LineIndex + 1)
+            else:
+                EdkLogger.error("Parser", FORMAT_INVALID, "%s not defined" % (Macro), ExtraData=self._CurrentLine, File=self.MetaFile, Line=self._LineIndex + 1)
         # Sometimes, we need to make differences between EDK and EDK2 modules 
         if Name == 'INF_VERSION':
             if re.match(r'0[xX][\da-f-A-F]{5,8}', Value):
diff --git a/BaseTools/Source/Python/Workspace/WorkspaceDatabase.py b/BaseTools/Source/Python/Workspace/WorkspaceDatabase.py
index e7bc87dc6b..06867219b7 100644
--- a/BaseTools/Source/Python/Workspace/WorkspaceDatabase.py
+++ b/BaseTools/Source/Python/Workspace/WorkspaceDatabase.py
@@ -1,7 +1,7 @@
 ## @file
 # This file is used to create a database used by build tool
 #
-# Copyright (c) 2008 - 2016, Intel Corporation. All rights reserved.<BR>
+# Copyright (c) 2008 - 2017, Intel Corporation. All rights reserved.<BR>
 # (C) Copyright 2016 Hewlett Packard Enterprise Development LP<BR>
 # This program and the accompanying materials
 # are licensed and made available under the terms and conditions of the BSD License
@@ -1830,6 +1830,8 @@ class InfBuildData(ModuleBuildClassObject):
             if self.AutoGenVersion < 0x00010005:
                 self.__Macros.update(GlobalData.gEdkGlobal)
                 self.__Macros.update(GlobalData.gGlobalDefines)
+            else:
+                self.__Macros.update(self.Defines)
         return self.__Macros
 
     ## Get architecture