diff --git a/MdePkg/Include/Ia32/Nasm.inc b/MdePkg/Include/Ia32/Nasm.inc
index fa42f9d3e9..c794d9ece3 100644
--- a/MdePkg/Include/Ia32/Nasm.inc
+++ b/MdePkg/Include/Ia32/Nasm.inc
@@ -1,6 +1,6 @@
 ;------------------------------------------------------------------------------
 ;
-; Copyright (c) 2019, Intel Corporation. All rights reserved.<BR>
+; Copyright (c) 2019 - 2021, Intel Corporation. All rights reserved.<BR>
 ; SPDX-License-Identifier: BSD-2-Clause-Patent
 ;
 ; Abstract:
@@ -32,3 +32,41 @@
 %macro INCSSP_EAX      0
     DB 0xF3, 0x0F, 0xAE, 0xE8
 %endmacro
+
+; NASM provides built-in macros STRUC and ENDSTRUC for structure definition.
+; For example, to define a structure called mytype containing a longword,
+; a word, a byte and a string of bytes, you might code
+;
+; struc   mytype
+;
+;  mt_long:      resd    1
+;  mt_word:      resw    1
+;  mt_byte:      resb    1
+;  mt_str:       resb    32
+;
+; endstruc
+;
+; Below macros are help to map the C types and the RESB family of pseudo-instructions.
+; So that the above structure definition can be coded as
+;
+; struc   mytype
+;
+;  mt_long:      CTYPE_UINT32    1
+;  mt_word:      CTYPE_UINT16    1
+;  mt_byte:      CTYPE_UINT8     1
+;  mt_str:       CTYPE_CHAR8     32
+;
+; endstruc
+%define CTYPE_UINT64    resq
+%define CTYPE_INT64     resq
+%define CTYPE_UINT32    resd
+%define CTYPE_INT32     resd
+%define CTYPE_UINT16    resw
+%define CTYPE_INT16     resw
+%define CTYPE_BOOLEAN   resb
+%define CTYPE_UINT8     resb
+%define CTYPE_CHAR8     resb
+%define CTYPE_INT8      resb
+
+%define CTYPE_UINTN     resd
+%define CTYPE_INTN      resd
diff --git a/MdePkg/Include/X64/Nasm.inc b/MdePkg/Include/X64/Nasm.inc
index e57a803c81..527f71e9eb 100644
--- a/MdePkg/Include/X64/Nasm.inc
+++ b/MdePkg/Include/X64/Nasm.inc
@@ -1,6 +1,6 @@
 ;------------------------------------------------------------------------------
 ;
-; Copyright (c) 2019, Intel Corporation. All rights reserved.<BR>
+; Copyright (c) 2019 - 2021, Intel Corporation. All rights reserved.<BR>
 ; SPDX-License-Identifier: BSD-2-Clause-Patent
 ;
 ; Abstract:
@@ -32,3 +32,41 @@
 %macro INCSSP_RAX      0
     DB 0xF3, 0x48, 0x0F, 0xAE, 0xE8
 %endmacro
+
+; NASM provides built-in macros STRUC and ENDSTRUC for structure definition.
+; For example, to define a structure called mytype containing a longword,
+; a word, a byte and a string of bytes, you might code
+;
+; struc   mytype
+;
+;  mt_long:      resd    1
+;  mt_word:      resw    1
+;  mt_byte:      resb    1
+;  mt_str:       resb    32
+;
+; endstruc
+;
+; Below macros are help to map the C types and the RESB family of pseudo-instructions.
+; So that the above structure definition can be coded as
+;
+; struc   mytype
+;
+;  mt_long:      CTYPE_UINT32    1
+;  mt_word:      CTYPE_UINT16    1
+;  mt_byte:      CTYPE_UINT8     1
+;  mt_str:       CTYPE_CHAR8     32
+;
+; endstruc
+%define CTYPE_UINT64    resq
+%define CTYPE_INT64     resq
+%define CTYPE_UINT32    resd
+%define CTYPE_INT32     resd
+%define CTYPE_UINT16    resw
+%define CTYPE_INT16     resw
+%define CTYPE_BOOLEAN   resb
+%define CTYPE_UINT8     resb
+%define CTYPE_CHAR8     resb
+%define CTYPE_INT8      resb
+
+%define CTYPE_UINTN     resq
+%define CTYPE_INTN      resq