diff --git a/MdePkg/Library/BaseLib/BaseLib.inf b/MdePkg/Library/BaseLib/BaseLib.inf
index facd9acb5b..858be7b026 100644
--- a/MdePkg/Library/BaseLib/BaseLib.inf
+++ b/MdePkg/Library/BaseLib/BaseLib.inf
@@ -480,9 +480,9 @@
   X64/CpuIdEx.S
   X64/CpuFlushTlb.S
   X64/CpuBreakpoint.S
-  Synchronization.c
-  SynchronizationMsc.c
-  SynchronizationGcc.c
+#  SynchronizationMsc.c  #|| INTC
+  SynchronizationMsc.c  #|| MSFT
+#  SynchronizationGcc.c  || GCC
 
 [Sources.IPF]
   Ipf/AccessGp.s
@@ -512,9 +512,9 @@
   Ipf/ia_64gen.h
   Ipf/asm.h
   Math64.c
-  Synchronization.c
-  SynchronizationMsc.c
-  SynchronizationGcc.c
+#  SynchronizationMsc.c  #|| INTC
+  SynchronizationMsc.c  #|| MSFT
+#  SynchronizationGcc.c  || GCC
 
 [Sources.EBC]
   Synchronization.c