diff --git a/MdeModulePkg/Include/UniversalPayload/SerialPortInfo.h b/MdeModulePkg/Include/UniversalPayload/SerialPortInfo.h
new file mode 100644
index 0000000000..87181f7634
--- /dev/null
+++ b/MdeModulePkg/Include/UniversalPayload/SerialPortInfo.h
@@ -0,0 +1,30 @@
+/** @file
+  This file defines the structure for serial port info.
+
+  Copyright (c) 2021, Intel Corporation. All rights reserved.<BR>
+  SPDX-License-Identifier: BSD-2-Clause-Patent
+
+  @par Revision Reference:
+    - Universal Payload Specification 0.75 (https://universalpayload.github.io/documentation/)
+**/
+
+#ifndef UNIVERSAL_PAYLOAD_SERIAL_PORT_INFO_H_
+#define UNIVERSAL_PAYLOAD_SERIAL_PORT_INFO_H_
+
+#include <UniversalPayload/UniversalPayload.h>
+
+#pragma pack(1)
+typedef struct {
+  UNIVERSAL_PAYLOAD_GENERIC_HEADER   Header;
+  BOOLEAN                            UseMmio;
+  UINT8                              RegisterStride;
+  UINT32                             BaudRate;
+  EFI_PHYSICAL_ADDRESS               RegisterBase;
+} UNIVERSAL_PAYLOAD_SERIAL_PORT_INFO;
+#pragma pack()
+
+#define UNIVERSAL_PAYLOAD_SERIAL_PORT_INFO_REVISION 1
+
+extern GUID gUniversalPayloadSerialPortInfoGuid;
+
+#endif //  UNIVERSAL_PAYLOAD_SERIAL_PORT_INFO_H_
diff --git a/MdeModulePkg/MdeModulePkg.dec b/MdeModulePkg/MdeModulePkg.dec
index 10602a8f79..ad84421cf3 100644
--- a/MdeModulePkg/MdeModulePkg.dec
+++ b/MdeModulePkg/MdeModulePkg.dec
@@ -422,6 +422,9 @@
   ## Include/UniversalPayload/ExtraData.h
   gUniversalPayloadExtraDataGuid = {0x15a5baf6, 0x1c91, 0x467d, {0x9d, 0xfb, 0x31, 0x9d, 0x17, 0x8d, 0x4b, 0xb4}}
 
+  ## Include/UniversalPayload/SerialPortInfo.h
+  gUniversalPayloadSerialPortInfoGuid = { 0xaa7e190d, 0xbe21, 0x4409, { 0x8e, 0x67, 0xa2, 0xcd, 0xf, 0x61, 0xe1, 0x70 } }
+
 [Ppis]
   ## Include/Ppi/AtaController.h
   gPeiAtaControllerPpiGuid       = { 0xa45e60d1, 0xc719, 0x44aa, { 0xb0, 0x7a, 0xaa, 0x77, 0x7f, 0x85, 0x90, 0x6d }}