diff --git a/MdePkg/Include/Ebc/ProcessorBind.h b/MdePkg/Include/Ebc/ProcessorBind.h
index 4e85175371..86b9b99408 100644
--- a/MdePkg/Include/Ebc/ProcessorBind.h
+++ b/MdePkg/Include/Ebc/ProcessorBind.h
@@ -121,14 +121,6 @@ typedef unsigned long         UINTN;
 #define EFIAPI    
 #endif
 
-///
-/// The Microsoft* C compiler can removed references to unreferenced data items
-///  if the /OPT:REF linker option is used. We defined a macro as this is a 
-///  a non standard extension. Currently not supported by the EBC compiler
-///
-#define GLOBAL_REMOVE_IF_UNREFERENCED
-
-
 /**
   Return the pointer to the first instruction of a function given a function pointer.
   On EBC architectures, these two pointer values are the same, 
diff --git a/MdePkg/Include/Ia32/ProcessorBind.h b/MdePkg/Include/Ia32/ProcessorBind.h
index a3567267d8..d70d3232cf 100644
--- a/MdePkg/Include/Ia32/ProcessorBind.h
+++ b/MdePkg/Include/Ia32/ProcessorBind.h
@@ -313,41 +313,10 @@ typedef INT32   INTN;
   #endif  
 #endif
 
-//
-// The Microsoft* C compiler can removed references to unreferenced data items
-//  if the /OPT:REF linker option is used. We defined a macro as this is a 
-//  a non standard extension
-//
-#if defined(_MSC_EXTENSIONS)
-  ///
-  /// Remove global variable from the linked image if there are no references to 
-  /// it after all compiler and linker optimizations have been performed.
-  ///
-  #define GLOBAL_REMOVE_IF_UNREFERENCED __declspec(selectany)
-#else
-  ///
-  /// Remove global variable from the linked image if there are no references to 
-  /// it after all compiler and linker optimizations have been performed.
-  ///
-  #define GLOBAL_REMOVE_IF_UNREFERENCED
-#endif
-
 //
 // For symbol name in GNU assembly code, an extra "_" is necessary
 //
 #if defined(__GNUC__)
-  ///
-  /// Private worker functions for ASM_PFX()
-  ///
-  #define _CONCATENATE(a, b)  __CONCATENATE(a, b)
-  #define __CONCATENATE(a, b) a ## b
-
-  ///
-  /// The __USER_LABEL_PREFIX__ macro predefined by GNUC represents the prefix
-  /// on symbols in assembly language.
-  ///
-  #define ASM_PFX(name) _CONCATENATE (__USER_LABEL_PREFIX__, name)
-
   ///
   /// For GNU assembly code, .global or .globl can declare global symbols.
   /// Define this macro to unify the usage.
diff --git a/MdePkg/Include/Ipf/ProcessorBind.h b/MdePkg/Include/Ipf/ProcessorBind.h
index c58588214f..1fdf8adde7 100644
--- a/MdePkg/Include/Ipf/ProcessorBind.h
+++ b/MdePkg/Include/Ipf/ProcessorBind.h
@@ -371,27 +371,6 @@ typedef INT64   INTN;
   #define EFIAPI
 #endif
 
-//
-// The Microsoft* C compiler can removed references to unreferenced data items
-//  if the /OPT:REF linker option is used. We defined a macro as this is a
-//  a non standard extension
-//
-#if defined(_MSC_EXTENSIONS)
-  ///
-  /// Remove global variable from the linked image if there are no references to 
-  /// it after all compiler and linker optimizations have been performed.
-  ///
-  ///
-  #define GLOBAL_REMOVE_IF_UNREFERENCED __declspec(selectany)
-#else
-  ///
-  /// Remove global variable from the linked image if there are no references to 
-  /// it after all compiler and linker optimizations have been performed.
-  ///
-  ///
-  #define GLOBAL_REMOVE_IF_UNREFERENCED
-#endif
-
 ///
 /// For GNU assembly code, .global or .globl can declare global symbols.
 /// Define this macro to unify the usage.
diff --git a/MdePkg/Include/X64/ProcessorBind.h b/MdePkg/Include/X64/ProcessorBind.h
index 027d8d0f59..026d6331b4 100644
--- a/MdePkg/Include/X64/ProcessorBind.h
+++ b/MdePkg/Include/X64/ProcessorBind.h
@@ -20,7 +20,6 @@
 ///
 #define MDE_CPU_X64
 
-
 //
 // Make sure we are using the correct packing rules per EFI specification
 //
@@ -375,43 +374,10 @@ typedef INT64   INTN;
   #define EFIAPI       
 #endif
 
-//
-// The Microsoft* C compiler can removed references to unreferenced data items
-//  if the /OPT:REF linker option is used. We defined a macro as this is a 
-//  a non standard extension
-//
-#if defined(_MSC_EXTENSIONS)
-  ///
-  /// Remove global variable from the linked image if there are no references to 
-  /// it after all compiler and linker optimizations have been performed.
-  ///
-  ///
-  #define GLOBAL_REMOVE_IF_UNREFERENCED __declspec(selectany)
-#else
-  ///
-  /// Remove global variable from the linked image if there are no references to 
-  /// it after all compiler and linker optimizations have been performed.
-  ///
-  ///
-  #define GLOBAL_REMOVE_IF_UNREFERENCED
-#endif
-
 //
 // For symbol name in GNU assembly code, an extra "_" is necessary
 //
 #if defined(__GNUC__)
-  ///
-  /// Private worker functions for ASM_PFX()
-  ///
-  #define _CONCATENATE(a, b)  __CONCATENATE(a, b)
-  #define __CONCATENATE(a, b) a ## b
-
-  ///
-  /// The __USER_LABEL_PREFIX__ macro predefined by GNUC represents the prefix
-  /// on symbols in assembly language.
-  ///
-  #define ASM_PFX(name) _CONCATENATE (__USER_LABEL_PREFIX__, name)
-
   ///
   /// For GNU assembly code, .global or .globl can declare global symbols.
   /// Define this macro to unify the usage.