diff --git a/cipher.c b/cipher.c
index 578763616..a72682a82 100644
--- a/cipher.c
+++ b/cipher.c
@@ -82,7 +82,9 @@ struct sshcipher {
 
 static const struct sshcipher ciphers[] = {
 #ifdef WITH_OPENSSL
+#ifndef OPENSSL_NO_DES
 	{ "3des-cbc",		8, 24, 0, 0, CFLAG_CBC, EVP_des_ede3_cbc },
+#endif
 	{ "aes128-cbc",		16, 16, 0, 0, CFLAG_CBC, EVP_aes_128_cbc },
 	{ "aes192-cbc",		16, 24, 0, 0, CFLAG_CBC, EVP_aes_192_cbc },
 	{ "aes256-cbc",		16, 32, 0, 0, CFLAG_CBC, EVP_aes_256_cbc },